| Mode of Action |
| Clinical Efficacy |
| Indications, Dosage & Administration |
| Presentation |
| |
 BIO-ENOX™, Enoxaparin Sodium Injection is a sterile aqueous solution containing, a low molecular weight heparin which has anti-thrombotic properties.
Mode of Action
BIO-ENOX™ in humans, Enoxaparin given at a dose of 1.5 mg/kg subcutaneously is characterized by a higher ratio of anti-Factor Xa to anti-Factor IIa activity. Maximum anti-Factor Xa and anti-thrombin (anti-Factor IIa) activities occur 3 to 5 hours after subcutaneous injection of Enoxaparin. Enoxaparin sodium is primarily metabolized in the liver by desulfation and/or depolymerization to lower molecular weight species with much reduced biological potency.
Clinical Efficacy
- 90% Bioavailability
- Prophylactic as well as treatment of DVT in patients undergoing high risk surgeries
- Shown significant efficacy in reducing the incidence of DVT (Deep Vein Thrombosis) & PE (Pulmonary Embolism)
Indications, Dosage & Administration |
40 mg * once daily
|
- Prophylaxis and treatment of high risk abdominal surgery
- Restricted or immobilized patient
|
1mg * /kg twice daily
|
- Unstable angina and Q-wave myocardial infarction
- Treatment of DVT with or with out Pulmonary embolism
|
30mg * twice daily
|
- Total / partial knee replacement surgery prophylactic
|
20mg * twice daily
|
- Total hip replacement surgery prophylactic
|
|
* To be administered subcutaneous route only
Presentation
BIO-ENOX™ is available in prefilled syringe as
- BIO-ENOX™ 60 mg
- BIO-ENOX™ 40 mg
- BIO-ENOX™ 20 mg
|
